Antifungal agent for primobolan only cycle application having a wide range of antifungal activity. At low concentrations terbinafine has fungicidal primobolan only cycle activity against dermatophytes . Activity against yeast fungi, depending on their type, may be a fungicidal or fungistatic.
Terbinafine specific alters the early stage of the biosynthesis of sterols in fungi occurring. This leads to a deficiency of ergosterol and to an intracellular accumulation of squalene, which primobolan only cycle causes death of fungal cells. Terbinafine action effected by the enzyme squalene epoxidase inhibiting located on the cell membrane of the fungus.
Terbinafine has no effect on the cytochrome P450 system in humans and, therefore, the metabolism of hormones or other drugs.
Indications for use:
Prevention and treatment of fungal skin infections, including fungal infections stop ( “mushroom” foot), jock itch (tinea cruris), fungal infections of the skin smooth body (tinea corporis), caused by dermatophytes such as Trichophyton (including, T.rubrum , T.mentagrophytes, T.verrucosum, T.violaceum), Microsporum canis and Epidermophyton floccosum.
yeast infections of the skin, mainly those which are caused by a native of Candida (eg, Candida albicans), in particular diaper rash.
colorful lichen (Pityriasis versicolor), called Pityrosporum orbiculare (also known as Malassezia furfur).
Hypersensitivity to terbinafine or to the other ingredients of the drug. Precautions: Hepatic and / or renal failure, alcoholism, depression of bone marrow hematopoiesis, tumors, metabolic diseases, limb occlusive vascular disease, children under 12 years of age (lack of sufficient clinical experience).
Pregnancy and lactation:
In experimental research teratogenic properties of terbinafine have been identified. So far no reports of any malformation when applying Atifina. However, as clinical experience with the drug in pregnant women is very limited, it should be used only on strict conditions.
Terbinafine is excreted in breast milk. However, in the case of nursing mother Atifina cream is absorbed through the skin a small amount of the active substance, so an adverse effect on the child is unlikely.
Dosage and administration:
Adults and children from 12 years.
Must be thoroughly clean and dry the affected area before applying the cream. The cream is applied 1 or 2 times per day to the affected thin layer of skin and adjacent portions of lightly rubbing. For infections involving intertrigo (under the breasts, in the interdigital spaces, between the buttocks, groin), cream application site can cover the gauze, especially at night.
|Disease||Dosage||length of treatment|
|Ringworm of the skin smooth and tinea cruris (in
including body ringworm, tinea shins)
|Twice daily (morning and evening)||1 Week|
|tinea pedis||• Twice a day, between the fingers (morning and evening)||• 1 Week|
|• the upper and side portions of the foot once a day||• 2 weeks|
|Fungal infections of the skin
caused by yeast
|Once a day||1 Week|
|colorful lichen||Once a day||2 weeks|
If after 1-2 weeks of treatment were observed signs of improvement, there should be verification of the diagnosis.
Cream Atifina Dosage in the elderly is not different from the above.
In the field of application of the drug can be redness, itching or burning. Allergic reactions.
No cases of overdose have been reported. If accidentally Atifin cream will be accepted inside, one can expect the development of side effects: headache, nausea, epigastric pain and dizziness.
Treatment: activated charcoal, if necessary – symptomatic supportive therapy.
Interactions with other medicines:
There are no drug interactions for terbinafine – cream is not known.
Reducing the severity of clinical manifestations are usually noted in the first days of treatment. In the case of irregular or premature treatment termination there is a risk of infection relapse.
Atifin Cream is for primobolan only cycle use only. Avoid getting it in your eyes, perhaps the appearance of irritation. In case of accidental contact with the drug in the eyes, they should immediately wash with running water, and in the case of persistent phenomena of irritation consult a doctor. With the development of allergic reactions need to stop the drug.
Cream for primobolan only cycle application of 1%. 15 g of cream in an aluminum tube. 1 tube in a carton box together with instructions for use.