Winstrol: negative effects

Back in 1988, the whole world of sports was shocked to learn that the famous Canadian sprinter Ben Johnson, who managed to do something that nobody had previously managed to win in the Olympic hundred-meter race of the previous champion Carl Lewis, was caught using anabolic steroids. Because of this, Johnson was removed from the competition for many years, because his test for doping showed that the athlete in the blood was found stanozolol. Also, Johnson took away the previously received gold medal and signed a contract worth more than eight million dollars. After several years, in 1990, the Anabolic Steroids Control Act was drafted and adopted, and as a result, such substances became classified as requiring special permission for the use of controlled substances.

Small efficiency at great risk

Stanozolol (or Winstrol, as it is called in the trading environment) is a weak steroid. Weak in terms of opportunities to increase the muscle mass of athletes who take it, but at the same time very popular and common among athletes and bodybuilders. Immediately after its appearance, Vinistrol was only sold in the form of tablets with a low dosage of 2 milligrams or in the form of an aqueous suspension in which one milliliter accounted for only fifty milligrams of the active substance. At the present time, this steroid can be found in any dosage and concentration, and the release of it organizes several brands at once. Previously, bodybuilders took Winistrol just before important competitions, because the substance can quickly improve the relief and muscle density. In 1995, a series of audiotapes from the magazine Media Media 2000 was released, one of which is devoted to an interview in which the narrator shares stories with the listeners about how the most hardy and successful runners achieved their success by taking small doses of Winstrol to prevent the occurrence of muscle loss, which Could arise as a result of catabolism, which is often amplified after the long runs.

Stanozolol is a chemical compound with the following structure: 17-methyl-5α-androstano (3,2-c) pyrazole-17β-ol and is classified as anabolic controlled steroid with the assigned number 302-96-5. Because of the impressive anabolic-androgenic ratio, this steroid belongs to highly anabolic substances. Paradoxically, but, in this case, the effect of it for increasing strength and muscle mass is not so great. Such surprisingly low efficacy of the drug can be explained by the fact that stanozolol itself is a sufficiently weak androgen, but it is significantly inferior to testosterone in effectiveness as an anabolic agent. If you compare stanozolol and testosterone, taken in equal doses, then in this comparison, stanozolol clearly loses to the enemy.

Surprisingly, despite its low efficiency, stanozolol is still quite popular. Perhaps the secret of such popularity of the substance lies in its reputation as an absolutely safe steroid, which, albeit not giving an overwhelming and as soon as possible effect, but also does not cause the body much harm. Of course, this opinion is mistaken. This steroid, although it does not cause strong side effects, like other high-androgenic steroids, but still not completely safe. Even vice versa: many specialists, having conducted appropriate clinical trials, come to the conclusion that stanozolol can be considered the most dangerous steroid that exists in the world today.

So is it dangerous stanozolol?

So what can you believe: the fact that stanozolol is almost safe or that a steroid is more difficult to find? It should be borne in mind that the action of the substance has not been thoroughly studied and is still multifaceted. At first glance, stanozolol should act on the same principle as other similar substances: cause increased aggressiveness, hair loss, acne. Drugs based on a highly allergenic form of testosterone, it is precisely this influence that exerts. But in reality it does not quite happen. Since stanozolol is a rather weak androgen, it does not increase the aggressiveness of living beings, but, on the contrary, suppresses it. Such data are confirmed by numerous experiments carried out on animals. Experimental specimens became so non-aggressive that they did not even react to physical provocations from other males that invaded their personal territory. These same experiments proved that the accepted stenozole was not perceived by the male sex glands (namely the seminal vesicles) as a substance replacing testosterone. The rats, which for a while received this steroid, eventually lost their ability to ejaculate and, in the end, stopped showing any sexual behavior. Researchers noticed a similar reaction in female individuals who, under the influence of the hormone estrogen, lost their sexual susceptibility.

So, judging by the effects of taking a steroid, displayed on behavior, then stanozolol can rather be called an antiandrogen than androgen. Since most often the reactions of the human body to certain substances do not differ too much from the reactions of the experimental samples, it can be confidently assumed that people taking stanozolol may have impaired sexual responsiveness, so that they may lose their competitive advantage over other individuals.

In addition to the above effects, taking stanozolol, according to numerous reports of specialists, can cause a blockage of normal brain function and various receptor systems, a violation of the action of anxioliotics and antidepressants. Many athletes who took some time steroids, talk about the period of depression, which abruptly begins immediately after the completion of the cycle of the drug. And experts studying this issue argue that stanozolol is contraindicated for people who are highly susceptible to such conditions. Therefore, despite the fact that stanozolol, unlike other steroid preparations, does not cause the appearance of so-called “steroid rage”, it is still quite dangerous for everyone who takes it, but in particular it is dangerous for people with unstable psyche, Who, by their nature, show a propensity for suicide or have psychological trauma.

Scientific research in the field of stanozolol

Referring to the chemical structure of the type of steroids in question, it should be noted that it is a derivative of dihydrotestosterone given by a steroid. This means that stanozolol is not a substrate of the aromatase enzyme, which is responsible for converting most androgens into estrogens (female sex hormones). Very few athletes taking stanozolol note estrogenic side effects if they used only one drug. However, it would be wrong to assume that there are no dangers of taking stanozolol here. Carrying out studies on laboratory mice, scientists have proved that this steroid has the property of accelerating puberty in female individuals in the pubertal period. Avoid this effect was obtained only if, in advance, before the course of stanozolol, experimental animals took an estrogen blocker. After the blocker, stanozolol still caused early changes in the vagina in mice, but these changes were quite insignificant. It is difficult to assert that this approach is also applied to people, because the doses of the drug used during the experiment are significantly less than those that athletes often take.

An experiment in mice and its results prompted scientists to hypothesize that stanozolol may act as an agonist for estrogen receptors in the same way as the more popular Novaldex (Tamoxifen). Stanozolol, although it does not belong to aromatase substrates, and therefore, has resistance to conversion to estrogen, still stimulates aromatase activity to some extent, and thus helps to convert other androgens into estrogen.

In another experiment, the experts tried to study the effect of stanozolol on skin cells in the laboratory. In the course of this experiment, they found that stanozolol in some cases demonstrates unique and unexpected results, which can not be explained solely by its connection with the hormone testosterone.

One of such results was the ability of the steroid to increase the production of collagen, enzymes and some prostaglandins in the skin. Trying to explain this phenomenon, experts have established that in fibroblasts of the skin (undeveloped, early skin cells), stanozolol is not replaced (not replaced) with norestestosterone (androgen), estradiol (estrogen) or dexamethasone (cortisol derivative). Instead, the steroid is replaced by progesterone, another female hormone. Progesterone has the ability to displace stanozolol from skin cell receptors, but it can not cause the same response itself. It turns out that the results of this experiment not only do not shed light on the action of stanozolol, but even more confuse the situation – it becomes absolutely unclear how stanozolol acts. Perhaps it interacts with other receptors, possibly interfering with the work of other hormones, and perhaps acting as a weak substituent.

None of the studies conducted has proven that stanozolol is an estrogenic or feminizing compound, and most people who take it can confirm this. This steroid is not estrogenic and makes it possible to tighten muscle tissue by minimizing the delay in the body’s fluid. In case of using the drug, gynecomastia can very rarely develop, but if you take stanozolol in combination with other agents, its negative impact on the body will be much more serious.

Other adverse effects of taking stanozolol

The above case, unfortunately, is far from being the only one of its kind. Even with a superficial analysis of specialized literature, one can find evidence of the following incidents associated with taking stanozolol: four heart attacks (two of which are fatal), one case of blood loss, safe for life, and one case of a sharp increase in heart rate. It should be noted that all these cases happened with young people, most often up to thirty years.

In the environment of athletes and bodybuilders it has long been known that taking stanozolol increases the possibility of a heart attack or heart attack, because the substance lowers “good” cholesterol in the blood and increases the concentration of “bad”. Women taking this steroid may have a masculinization effect, serious bleeding can occur (starting with banal nosebleeds and ending with esophageal varicose veins that is life-threatening), the risk of injury to tendons increases.

Stanozolol is easily detected by the analysis of hair or urine, and the remains of the substance remain in the human body for several months after the completion of the drug course. It is proven that this steroid inhibits the production of testosterone by the body, lowers the level of the androgen transporter protein in the blood.

Conclusion

Stanozolol, better known as Winstrol, is a popular steroid today. Most of those athletes who take it, absolutely sure that it does not do much harm to the body. Despite the fact that stanozolol does not demonstrate a clear risk of severe estrogenic and androgenic side effects, it is far from as safe as it seems. There is a lot of evidence that taking this medication negatively affects the work of various systems of the human body. The results of the conducted studies convincingly prove that this steroid substance mimics the effects of the hormone estrogen, lowers the libido, can promote the emergence and development of various mental disorders, weakens the healthy aggression and sexual function, quite often causes damage to the liver cells, and can lead to fatal outcome.

Typically, bodybuilders take up to a hundred milligrams of stanozolol a day, but even taking six to ten milligrams a day can inflict irreparable damage on your body. Considering the fact that at the moment there are a lot of different steroids known, many of which have much less side effects and risks than stanozolol, if you are going to use this drug, think about whether the game is worth the candle. comprare steroidi steroidi online steroidi anabolizzanti shop